The mitosis to meiosis transition requires dynamic changes in gene expression, but whether and how the mitotic transcriptional machinery is regulated during this transition is unknown.In budding yeast, SBF and MBF transcription factors initiate the mitotic gene expression program.Here, we report two mechanisms that work together to restrict SBF act

Prospect Theory (PT) and Constant-Relative-Risk-Aversion (CRRA) preferences have clear-cut and very different implications for the optimal asset allocation between a riskless asset and a risky stock as a function of the investment horizon.While CRRA implies that the Wire Strippers optimal allocation is independent of the horizon, we show that PT im

The Domain Name System (DNS) is a fundamental component of the internet, responsible for resolving domain names into IP addresses.DNS servers are typically categorized into four types: recursive resolvers, root name servers, Top-Level Domain (TLD) name servers, and authoritative name servers.The latter three types of servers store actual records, w

This paper presents an overview of the status and future prospects of fuel-cell electric vehicles (FC-EVs).As global concerns about emissions escalate, FC-EVs have emerged as a promising substitute for traditional internal combustion engine vehicles.This paper discusses the fundamentals of fuel-cell technology considering the major types of fuel ce

Abstract Necroptosis is a form of regulated cell death that has been implicated in multiple diseases.TNF-induced necroptosis is regulated by necrosomes, complexes consisting of RIPK1, RIPK3 and MLKL.In this study, by screening of a small-compound library, we identified dozens of compounds that Cereal inhibited TNF-induced necroptosis.According to t